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PIK-III

Product Specifications

CAS Number

1383716-40-2

Synonyms

VPS34-IN2

Target

Autophagy

Applications

Autophagy

Smiles

C1CC1CC2=NC (=NC=C2C3=NC (=NC=C3) NC4=CC=NC=C4) N

Molecular Formula

C17H17N7

Additionnal Information

PIK-III (VPS34-IN2), which is a selective inhibitor of ​VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI (3) Kδ are 0.018 μM and 1.2 μM respectively.

Storage Conditions

2 years -80 in solvent

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