Savolitinib (AZD6094)
Product Specifications
CAS Number
1313725-88-0
Synonyms
HMPL-504, Volitinib
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CC (C1=CN2C=CN=C2C=C1) N3C4=NC (=CN=C4N=N3) C5=CN (N=C5) C
Molecular Formula
C17H15N9
Additionnal Information
Savolitinib (Volitinib, AZD6094, HMPL-504) is a novel, potent, and selective MET inhibitor currently in clinical development in various indications, including PRCC. The IC50 values of this compound for c-Met and p-Met are 5 nM and 3 nM, respectively. It shows exquisite selectivity for c-Met over 274 kinase.
Storage Conditions
2 years -80 in solvent
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