Picropodophyllin (PPP)
Product Specifications
CAS Number
477-47-4
Synonyms
AXL1717
Target
IGF-1R
Applications
Protein Tyrosine Kinase
Smiles
COC1=CC (=CC (=C1OC) OC) C2C3C (COC3=O) C (C4=CC5=C (C=C24) OCO5) O
Molecular Formula
C22H22O8
Additionnal Information
Picropodophyllin (PPP, AXL1717) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR (FGF-R, PDGF-R, OR EGF-R) . Picropodophyllin (PPP) induces apoptosis with antineoplastic activity.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1316021-01 0.02 mg (E-Coli)
Recombinant Caulobacter crescentus UPF0434 protein CC_0108 (CC_0108)
Sign In for Pricing
View Details MBS1316021-02 0.1 mg (E-Coli)
Recombinant Caulobacter crescentus UPF0434 protein CC_0108 (CC_0108)
Sign In for Pricing
View Details MBS1316021-03 0.02 mg (Yeast)
Recombinant Caulobacter crescentus UPF0434 protein CC_0108 (CC_0108)
Sign In for Pricing
View Details MBS1316021-04 0.1 mg (Yeast)
Recombinant Caulobacter crescentus UPF0434 protein CC_0108 (CC_0108)
Sign In for Pricing
View Details MBS1316021-05 0.02 mg (Baculovirus)
Recombinant Caulobacter crescentus UPF0434 protein CC_0108 (CC_0108)
Sign In for Pricing
View Details