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Zoligratinib (Debio-1347)

Product Specifications

CAS Number

1265229-25-1

Synonyms

CH5183284, FF284

Target

FGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1=NC2=C (N1) C=C (C=C2) N3C (=C (C=N3) C (=O) C4=CC5=CC=CC=C5N4) N

Molecular Formula

C20H16N6O

Additionnal Information

Zoligratinib (Debio-1347, CH5183284, FF284) is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Phase 1.

Storage Conditions

2 years -80 in solvent

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