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Telaglenastat (CB-839)

Product Specifications

CAS Number

1439399-58-2

Target

Glutaminase

Applications

Proteases

Smiles

C1=CC=NC (=C1) CC (=O) NC2=NN=C (S2) CCCCC3=NN=C (C=C3) NC (=O) CC4=CC (=CC=C4) OC (F) (F) F

Molecular Formula

C26H24F3N7O3S

Additionnal Information

Telaglenastat (CB-839) is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC. CB-839 (Telaglenastat) inudces autophagy and has antitumor activity. Phase 1.

Storage Conditions

2 years -80 in solvent

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