Pilaralisib (XL147)
Product Specifications
CAS Number
934526-89-3
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
CC (C) (C (=O) NC1=CC (=CC=C1) S (=O) (=O) NC2=NC3=CC=CC=C3N=C2NC4=C (C=CC (=C4) OC) Cl) N
Molecular Formula
C25H25ClN6O4S
Additionnal Information
Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Phase 1/2.
Storage Conditions
2 years -80 in solvent
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