What is the catalog number for 3PO?

The catalog number for 3PO is C12835-5mg.

What sizes are available for 3PO?

3PO is available in the following size(s): 5 mg.

3PO is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for 3PO?

3PO is requires dry ice shipping.

3PO

Product Specifications

CAS Number

18550-98-6

Synonyms

3- (3-pyridinyl) -1- (4-pyridinyl) -2-propen-1-one

Target

PFKFB

Applications

Apoptosis

Smiles

C1=CC (=CN=C1) C=CC (=O) C2=CC=NC=C2

Molecular Formula

C13H10N2O

Additionnal Information

3PO (3- (3-pyridinyl) -1- (4-pyridinyl) -2-propen-1-one) is a small-molecule inhibitor of PFKFB3 with an IC50 of 22.9 μM for recombinant human PFKFB3 protein and does not inhibit PFK-1 activity. It suppresses glucose uptake, and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH.