LDC1267

Product Specifications

CAS Number

1361030-48-9

Target

Tyro3

Applications

Protein Tyrosine Kinase

Smiles

CCOC1=CN (N=C1C (=O) NC2=CC (=C (C=C2) OC3=C4C=C (C (=CC4=NC=C3) OC) OC) F) C5=C (C=C (C=C5) F) C

Molecular Formula

C30H26F2N4O5

Additionnal Information

LDC1267 is a highly selective TAM kinase inhibitor with IC50 of <5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.

Storage Conditions

2 years -80 in solvent

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