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Cerdulatinib (PRT062070) hydrochloride

Product Specifications

CAS Number

1369761-01-2

Synonyms

PRT2070 hydrochloride

Target

JAK

Applications

Angiogenesis

Smiles

CCS (=O) (=O) N1CCN (CC1) C2=CC=C (C=C2) NC3=NC=C (C (=N3) NC4CC4) C (=O) N.Cl

Molecular Formula

C20H28ClN7O3S

Additionnal Information

Cerdulatinib (PRT-062070, PRT2070) hydrochloride is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.

Storage Conditions

2 years -80 in solvent

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