Niraparib tosylate
Product Specifications
CAS Number
1038915-73-9
Synonyms
MK 4827 tosylate
Target
PARP
Applications
DNA Damage/DNA Repair
Smiles
CC1=CC=C (C=C1) S (=O) (=O) O.C1CC (CNC1) C2=CC=C (C=C2) N3C=C4C=CC=C (C4=N3) C (=O) N
Molecular Formula
C19H20N4O.C7H8O3S
Additionnal Information
Niraparib tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death.
Storage Conditions
2 years -80 in solvent
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