Niraparib tosylate

Product Specifications

CAS Number

1038915-73-9

Synonyms

MK 4827 tosylate

Target

PARP

Applications

DNA Damage/DNA Repair

Smiles

CC1=CC=C (C=C1) S (=O) (=O) O.C1CC (CNC1) C2=CC=C (C=C2) N3C=C4C=CC=C (C4=N3) C (=O) N

Molecular Formula

C19H20N4O.C7H8O3S

Additionnal Information

Niraparib tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death.

Storage Conditions

2 years -80 in solvent

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