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UNC2025 HCl

Product Specifications

CAS Number

2070015-17-5

Synonyms

UNC2025 hydrochloride

Target

Axl

Applications

Protein Tyrosine Kinase

Smiles

CCCCNC1=NC=C2C (=CN (C2=N1) C3CCC (CC3) O) C4=CC=C (C=C4) CN5CCN (CC5) C.Cl

Molecular Formula

C28H41ClN6O

Additionnal Information

UNC2025 HCl is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.

Storage Conditions

2 years -80 in solvent

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