What is the catalog number for WH-4-023?

The catalog number for WH-4-023 is C12782-10mM/1mL.

What sizes are available for WH-4-023?

WH-4-023 is available in the following size(s): 10 mM/1mL.

Is WH-4-023 in stock?

WH-4-023 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for WH-4-023?

WH-4-023 is requires dry ice shipping.

WH-4-023

Product Specifications

CAS Number

837422-57-8

Synonyms

KIN001-112, KIN112, Dual LCK/SRC inhibitor

Target

Src

Applications

Protein Tyrosine Kinase

Smiles

CC1=C (C (=CC=C1) C) OC (=O) N (C2=C (C=C (C=C2) OC) OC) C3=NC (=NC=C3) NC4=CC=C (C=C4) N5CCN (CC5) C

Molecular Formula

C32H36N6O4

Additionnal Information

WH-4-023 (KIN001-112, KIN112, Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.