SAR125844
Product Specifications
CAS Number
1116743-46-4
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
C1COCCN1CCNC (=O) NC2=NC3=C (S2) C=C (C=C3) SC4=NN=C5N4N=C (C=C5) C6=CC=C (C=C6) F
Molecular Formula
C25H23FN8O2S2
Additionnal Information
SAR125844 is a potent intravenously active and highly selective Met (c-Met) kinase inhibitor, displaying nanomolar activity against the wild-type kinase (IC50 value of 4.2 nmol/L) and H1094Y, Y1235D, M1250T, L1195V, and D1228H kinase domain mutants (IC50 values of 0.22, 1.7, 6.5, 65, and 81 nmol/L, respectively) .
Storage Conditions
3 years -20°C powder
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