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AT13148

Product Specifications

CAS Number

1056901-62-2

Target

Akt

Applications

PI3K/Akt/mTOR

Smiles

C1=CC (=CC=C1C2=CNN=C2) C (CN) (C3=CC=C (C=C3) Cl) O

Molecular Formula

C17H16ClN3O

Additionnal Information

AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Phase 1.

Storage Conditions

2 years -80 in solvent

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