Piperlongumine
Product Specifications
CAS Number
20069-09-4
Synonyms
PPLGM, Piplartine
Target
ROS
Applications
NF-κB
Smiles
COC1=CC (=CC (=C1OC) OC) C=CC (=O) N2CCC=CC2=O
Molecular Formula
C17H19NO5
Additionnal Information
Piperlongumine (PPLGM, Piplartine), a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1; also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells.
Storage Conditions
2 years -80 in solvent
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