G-749
Product Specifications
CAS Number
1457983-28-6
Target
FLT3
Applications
Protein Tyrosine Kinase
Smiles
CN1CCC (CC1) NC2=NC3=C (C (=O) NC=C3Br) C (=N2) NC4=CC=C (C=C4) OC5=CC=CC=C5
Molecular Formula
C25H25BrN6O2
Additionnal Information
G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.
Storage Conditions
2 years -80 in solvent
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