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G-749

Product Specifications

CAS Number

1457983-28-6

Target

FLT3

Applications

Protein Tyrosine Kinase

Smiles

CN1CCC (CC1) NC2=NC3=C (C (=O) NC=C3Br) C (=N2) NC4=CC=C (C=C4) OC5=CC=CC=C5

Molecular Formula

C25H25BrN6O2

Additionnal Information

G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.

Storage Conditions

2 years -80 in solvent

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