Vactosertib (TEW-7197)
Product Specifications
CAS Number
1352608-82-2
Synonyms
EW-7197
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
CC1=NC (=CC=C1) C2=C (N=C (N2) CNC3=CC=CC=C3F) C4=CN5C (=NC=N5) C=C4
Molecular Formula
C22H18FN7
Additionnal Information
Vactosertib (TEW-7197, EW-7197) is a highly potent, selective, and orally bioavailable TGF-β receptor ALK4/ALK5 inhibitor with IC50 of 13 nM and 11 nM, respectively. Phase 1.
Storage Conditions
2 years -80 in solvent
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