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Vactosertib (TEW-7197)

Product Specifications

CAS Number

1352608-82-2

Synonyms

EW-7197

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

CC1=NC (=CC=C1) C2=C (N=C (N2) CNC3=CC=CC=C3F) C4=CN5C (=NC=N5) C=C4

Molecular Formula

C22H18FN7

Additionnal Information

Vactosertib (TEW-7197, EW-7197) is a highly potent, selective, and orally bioavailable TGF-β receptor ALK4/ALK5 inhibitor with IC50 of 13 nM and 11 nM, respectively. Phase 1.

Storage Conditions

2 years -80 in solvent

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