FR 180204
Product Specifications
CAS Number
865362-74-9
Target
ERK
Applications
MAPK
Smiles
C1=CC=C (C=C1) C2=NN3C=CC=CC3=C2C4=CC5=C (NN=C5N=N4) N
Molecular Formula
C18 H13 N7
Additionnal Information
FR 180204 is an ATP-competitive, selective ERK inhibitor with Ki of 0.31 μM and 0.14 μM for ERK1 And ERK2, respectively. It is 30-fold less potent against the related kinase p38α and failed to inhibit any kinases (MEK1, MKK4, IKKα, PKCα, Src, Syc, and PDGFα) at less than 30 μM.
Storage Conditions
2 years -80 in solvent
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