What is the catalog number for FR 180204?

The catalog number for FR 180204 is C12751-5mg.

What sizes are available for FR 180204?

FR 180204 is available in the following size(s): 5 mg.

Is FR 180204 in stock?

FR 180204 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for FR 180204?

FR 180204 is requires dry ice shipping.

FR 180204

Product Specifications

CAS Number

865362-74-9

Target

ERK

Applications

MAPK

Smiles

C1=CC=C (C=C1) C2=NN3C=CC=CC3=C2C4=CC5=C (NN=C5N=N4) N

Molecular Formula

C18 H13 N7

Additionnal Information

FR 180204 is an ATP-competitive, selective ERK inhibitor with Ki of 0.31 μM and 0.14 μM for ERK1 And ERK2, respectively. It is 30-fold less potent against the related kinase p38α and failed to inhibit any kinases (MEK1, MKK4, IKKα, PKCα, Src, Syc, and PDGFα) at less than 30 μM.