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Afuresertib (GSK2110183)

Product Specifications

CAS Number

1047644-62-1

Target

Akt

Applications

PI3K/Akt/mTOR

Smiles

CN1C (=C (C=N1) Cl) C2=C (SC (=C2) C (=O) NC (CC3=CC (=CC=C3) F) CN) Cl

Molecular Formula

C18H17Cl2FN4OS

Additionnal Information

Afuresertib (GSK2110183) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.

Storage Conditions

2 years -80 in solvent

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