Afuresertib (GSK2110183)
Product Specifications
CAS Number
1047644-62-1
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
CN1C (=C (C=N1) Cl) C2=C (SC (=C2) C (=O) NC (CC3=CC (=CC=C3) F) CN) Cl
Molecular Formula
C18H17Cl2FN4OS
Additionnal Information
Afuresertib (GSK2110183) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.
Storage Conditions
2 years -80 in solvent
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