GNF-5837
Product Specifications
CAS Number
1033769-28-6
Target
Trk receptor
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=C (C=C1) NC (=O) NC2=C (C=CC (=C2) C (F) (F) F) F) NC3=CC4=C (C=C3) C (=CC5=CC=CN5) C (=O) N4
Molecular Formula
C28H21F4N5O2
Additionnal Information
GNF-5837 is a selective, and orally bioavailable pan-TRK inhibitor for TrkA, and TrkB with IC50 of 8 nM, and 12 nM, respectively.
Storage Conditions
2 years -80 in solvent
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