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(S) -crizotinib

Product Specifications

CAS Number

1374356-45-2

Target

MTH1

Applications

DNA Damage/DNA Repair

Smiles

CC (C1=C (C=CC (=C1Cl) F) Cl) OC2=C (N=CC (=C2) C3=CN (N=C3) C4CCNCC4) N

Molecular Formula

C21H22Cl2FN5O

Additionnal Information

(S) -crizotinib, the (S) -enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM in a cell-free assay.

Storage Conditions

2 years -80 in solvent

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