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FTI 277 HCl

Product Specifications

CAS Number

180977-34-8

Target

Transferase

Applications

Metabolism

Smiles

COC (=O) C (CCSC) NC (=O) C1=C (C=C (C=C1) NCC (CS) N) C2=CC=CC=C2.Cl

Molecular Formula

C22H30ClN3O3S2

Additionnal Information

FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.

Storage Conditions

2 years -80 in solvent

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