Rocaglamide
Product Specifications
CAS Number
84573-16-0
Synonyms
Roc-A
Target
HSP (HSP90)
Applications
Cytoskeletal Signaling
Smiles
CN (C) C (=O) C1C (C2 (C (C1O) (C3=C (O2) C=C (C=C3OC) OC) O) C4=CC=C (C=C4) OC) C5=CC=CC=C5
Molecular Formula
C29H31NO7
Additionnal Information
Rocaglamide (Roc-A), isolated from Aglaia species, is a potent inhibitor of heat shock factor 1 (HSF1) activation with IC50 of ~50 nM for HSF1. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also inhibits NF-κB activity. Rocaglamide exhibits anti-tumor activity.
Storage Conditions
3 years -20°C powder
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