What is the catalog number for AMG 232 (KRT-232)?

The catalog number for AMG 232 (KRT-232) is C12677-5mg.

What sizes are available for AMG 232 (KRT-232)?

AMG 232 (KRT-232) is available in the following size(s): 5 mg.

Is AMG 232 (KRT-232) in stock?

AMG 232 (KRT-232) is currently made to order / not held in immediate stock. Contact us for lead time.

AMG 232 (KRT-232)

Product Specifications

CAS Number

1352066-68-2

Synonyms

Navtemadlin

Target

MDM2/MDMX

Applications

Apoptosis

Molecular Formula

C28H35Cl2NO5S

Additionnal Information

AMG 232 (Navtemadlin) is a potential, selective inhibitor of the MDM2–p53 interaction, with an IC50 of 0.6 nM and binds to MDM2 with a Kd of 0.045 nM. It also demonstrated antitumor activity in vivo in a variety of tumor types with different genetic backgrounds.