4EGI-1
Product Specifications
CAS Number
315706-13-9
Target
EIF
Applications
Cell Cycle
Smiles
C1=CC=C (C (=C1) CC (=NNC2=NC (=CS2) C3=CC (=C (C=C3) Cl) Cl) C (=O) O) [N+] (=O) [O-]
Molecular Formula
C18H12Cl2N4O4S
Additionnal Information
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM. 4EGI-1 specifically inhibits the function of mTOR by blocking the activation of 4E-BP1. 4EGI-1 induces apoptosis.
Storage Conditions
2 years -80 in solvent
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