EPZ004777
Product Specifications
CAS Number
1338466-77-5
Target
Histone Methyltransferase
Applications
Epigenetics
Smiles
CC (C) N (CCCNC (=O) NC1=CC=C (C=C1) C (C) (C) C) CC2C (C (C (O2) N3C=CC4=C (N=CN=C43) N) O) O
Molecular Formula
C28H41N7O4
Additionnal Information
EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM in a cell-free assay and demonstrates >1,200-fold selectivity for DOT1L over all other tested PMTs. EPZ004777 induces apoptosis.
Storage Conditions
2 years -80 in solvent
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