URMC-099
Product Specifications
CAS Number
1229582-33-5
Target
LRRK2
Applications
Autophagy
Smiles
CN1CCN (CC1) CC2=CC=C (C=C2) C3=CC4=C (NC=C4C5=CC6=C (C=C5) NC=C6) N=C3
Molecular Formula
C27H27N5
Additionnal Information
URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM. URMC-099 also inhibits ABL1 with IC50 of 6.8 nM. URMC-099 induces autophagy.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15361706 1 Vial
Lentiviral human ZNF674 sgRNA gene knockout kit - Lentiviral human ZNF674 sgRNA gene knockout kit (plasmid)
Sign In for Pricing
View Details 041317-ML750 100 µL
RTDR1, NT (RTDR1, Rhabdoid tumor deletion region protein 1) (MaxLight 750) discontinued
Sign In for Pricing
View Details