BAY 87-2243
Product Specifications
CAS Number
1227158-85-1
Target
HIF
Applications
Angiogenesis
Smiles
CC1=CC (=NN1CC2=CC (=NC=C2) N3CCN (CC3) C4CC4) C5=NC (=NO5) C6=CC=C (C=C6) OC (F) (F) F
Molecular Formula
C26H26F3N7O2
Additionnal Information
BAY 87-2243 is a potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor. BAY 87-2243 inhibits mitochondrial complex I activity, thus triggering a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis. BAY 87-2243 exerts antitumor activity. Phase 1.
Storage Conditions
2 years -80 in solvent
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