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TAK-632

Product Specifications

CAS Number

1228591-30-7

Target

Raf

Applications

MAPK

Smiles

C1CC1C (=O) NC2=NC3=C (S2) C (=C (C=C3) OC4=CC (=C (C=C4) F) NC (=O) CC5=CC (=CC=C5) C (F) (F) F) C#N

Molecular Formula

C27H18F4N4O3S

Additionnal Information

TAK-632 is a potent pan-Raf inhibitor with IC50 of 8.3 nM and 1.4 nM for B-Raf (wt) and C-Raf in cell-free assays, respectively, showing less or no inhibition against other tested kinases.

Storage Conditions

2 years -80 in solvent

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