NMS-873
Product Specifications
CAS Number
1418013-75-8
Target
P97
Applications
Ubiquitin
Smiles
CC1=C (C=CC (=C1) OCC2=NN=C (N2C3=CN=CC=C3) SC4CCCC4) C5=CC=C (C=C5) S (=O) (=O) C
Molecular Formula
C27H28N4O3S2
Additionnal Information
NMS-873 is an allosteric and specific p97 inhibitor with IC50 of 30 nM that demonstrates potent selectivity for VCP/p97 compared to a panel of other AAA ATPases, Hsp90, and 53 additional analyzed kinases (IC50s >10 μM) .
Storage Conditions
2 years -80 in solvent
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