SGI-1027
Product Specifications
CAS Number
1020149-73-8
Synonyms
DNA Methyltransferase Inhibitor II
Target
DNA Methyltransferase
Applications
Epigenetics
Smiles
CC1=CC (=NC (=N1) N) NC2=CC=C (C=C2) NC (=O) C3=CC=C (C=C3) NC4=CC=NC5=CC=CC=C54
Molecular Formula
C27H23N7O
Additionnal Information
SGI-1027 (DNA Methyltransferase Inhibitor II) is a DNMT inhibitor with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B in cell-free assays, respectively. SGI‐1027 induces apoptosis.
Storage Conditions
2 years -80 in solvent
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