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Fostemsavir

Product Specifications

CAS Number

864953-29-7

Synonyms

BMS-663068, Rukobia

Target

Gp120/CD4

Applications

Immunology & Inflammation

Smiles

COC1=CN=C ([N]2C=NC (=N2) C) C3=C1C (=C[N]3CO[P] (O) (O) =O) C (=O) C (=O) N4CCN (CC4) C (=O) C5=CC=CC=C5

Molecular Formula

C25H26N7O8P

Additionnal Information

Fostemsavir (BMS-663068, Rukobia), the phosphonooxymethyl prodrug of BMS626529, is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM.

Storage Conditions

2 years -80 in solvent

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