Losmapimod
Product Specifications
CAS Number
585543-15-3
Synonyms
GW856553X, GSK-AHAB
Target
P38 MAPK
Applications
MAPK
Smiles
CC1=C (C=C (C=C1F) C (=O) NC2CC2) C3=NC=C (C=C3) C (=O) NCC (C) (C) C
Molecular Formula
C22 H26 F N3 O2
Additionnal Information
Losmapimod is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. P38 MAPKs are involved in cell differentiation, apoptosis and autophagy. Phase 3.
Storage Conditions
2 years -80 in solvent
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