What is the catalog number for BIO?

The catalog number for BIO is C12517-1g.

What sizes are available for BIO?

BIO is available in the following size(s): 1 g.

BIO is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for BIO?

BIO is requires dry ice shipping.

BIO

Product Specifications

CAS Number

667463-62-9

Synonyms

GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime, MLS 2052

Target

GSK-3

Applications

PI3K/Akt/mTOR

Smiles

C1=CC=C2C (=C1) C (=C (N2) C3=C (NC4=C3C=CC (=C4) Br) O) N=O

Molecular Formula

C16H10BrN3O2

Additionnal Information

BIO (GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime, MLS 2052) is a specific inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/β in a cell-free assay, shows >16-fold selectivity over CDK5, also a pan-JAK inhibitor with IC50 of 30 nM for Tyk2. BIO induces apoptosis in human melanoma cells.