Olverembatinib (GZD824) dimesylate
Product Specifications
CAS Number
1421783-64-3
Synonyms
HQP1351 dimesylate
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=C (C=C1) C (=O) NC2=CC (=C (C=C2) CN3CCN (CC3) C) C (F) (F) F) C#CC4=CC5=C (NN=C5) N=C4.CS (=O) (=O) O.CS (=O) (=O) O
Molecular Formula
C29H27F3N6O.2CH4O3S
Additionnal Information
Olverembatinib (GZD824) dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl (WT) and Bcr-Abl (T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.
Storage Conditions
2 years -80 in solvent
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