Molibresib (I-BET-762)
Product Specifications
CAS Number
1260907-17-2
Synonyms
GSK525762, GSK525762A
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CCNC (=O) CC1C2=NN=C (N2C3=C (C=C (C=C3) OC) C (=N1) C4=CC=C (C=C4) Cl) C
Molecular Formula
C22H22ClN5O2
Additionnal Information
Molibresib (I-BET-762, GSK525762, GSK525762A) is an inhibitor for BET proteins with IC50 of ~35 nM in a cell-free assay, suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation, highly selective over other bromodomain-containing proteins.
Storage Conditions
2 years -80 in solvent
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