SEW 2871
Product Specifications
CAS Number
256414-75-2
Target
S1P Receptor
Applications
GPCR & G Protein
Smiles
C1=CC=C (C=C1) C2=C (SC (=C2) C3=NC (=NO3) C4=CC (=CC=C4) C (F) (F) F) C (F) (F) F
Molecular Formula
C20H10F6N2OS
Additionnal Information
SEW2871 is an orally active, potent, and highly selective agonist of the sphingosine-1-phosphate type 1 receptor (S1P1) with an EC50 of 13.8 nM. It activates ERK, Akt, and Rac signalling pathways and induces S1P1 internalization and recycling.
Storage Conditions
2 years -80 in solvent
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