Setanaxib (GKT137831)
Product Specifications
CAS Number
1218942-37-0
Synonyms
GKT831
Target
NADPH-oxidase
Applications
Immunology & Inflammation
Smiles
CN1C (=O) C=C2C (=C1C3=CC (=CC=C3) N (C) C) C (=O) N (N2) C4=CC=CC=C4Cl
Molecular Formula
C21H19ClN4O2
Additionnal Information
Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
44288156 3x 1.0 µg DNA
SLC7A9 CRISPR All-in-one AAV vector set (with saCas9)(Rat)
Sign In for Pricing
View Details 
GTR15362524 1 Vial
Lentiviral human GET1-SH3BGR sgRNA gene knockout kit - Lentiviral human GET1-SH3BGR sgRNA gene knockout kit (100)
Sign In for Pricing
View Details 
K0920202 1.0 µg DNA
GUCA1A sgRNA CRISPR Lentivector (Human) (Target 1)
Sign In for Pricing
View Details 299129 50 µg
DMBT1 (Deleted in Malignant Brain Tumors 1, Muclin, Crp-Ductin, Vomeroglandin)
Sign In for Pricing
View Details