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C646

Product Specifications

CAS Number

328968-36-1

Target

Histone Acetyltransferase

Applications

Epigenetics

Smiles

CC1=CC (=C (C=C1C) [N+] (=O) [O-]) C2=CC=C (O2) C=C3C (=NN (C3=O) C4=CC=C (C=C4) C (=O) O) C

Molecular Formula

C24H19N3O6

Additionnal Information

C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM in a cell-free assay. Preferentially selective for p300 versus other acetyltransferases. C646 induces cell cycle arrest, apoptosis and autophagy.

Storage Conditions

2 years -80 in solvent

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