ML347
Product Specifications
CAS Number
1062368-49-3
Synonyms
LDN-193719
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
COC1=CC=C (C=C1) C2=CN3C (=C (C=N3) C4=C5C=CC=NC5=CC=C4) N=C2
Molecular Formula
C22 H16 N4 O
Additionnal Information
ML347 (LDN-193719) is a selective BMP receptor inhibitor with IC50 of 32 nM for ALK2, >300-fold selectivity over ALK3. Also inhibits ALK1 activity with IC50 of 46 nM.
Storage Conditions
2 years -80 in solvent
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