AZD1080
Product Specifications
CAS Number
612487-72-6
Target
GSK-3
Applications
PI3K/Akt/mTOR
Smiles
C1COCCN1CC2=CN=C (C=C2) C3=C (NC4=C3C=C (C=C4) C#N) O
Molecular Formula
C19H18N4O2
Additionnal Information
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows >14-fold selectivity against CDK2, CDK5, CDK1 and Erk2.
Storage Conditions
2 years -80 in solvent
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