BMS-911543

Product Specifications

CAS Number

1271022-90-2

Target

JAK

Applications

Angiogenesis

Smiles

CCN1C (=CC2=C3C (=C (N=C21) NC4=NN (C (=C4) C) C) N=CN3C) C (=O) N (C5CC5) C6CC6

Molecular Formula

C23H28N8O

Additionnal Information

BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.

Storage Conditions

2 years -80 in solvent

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