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GLPG0634 analogue

Product Specifications

CAS Number

1206101-20-3

Target

JAK

Applications

Angiogenesis

Smiles

C1CC1C (=O) NC2=NN3C (=N2) C=CC=C3C4=CC=C (C=C4) CN5CCS (=O) (=O) CC5

Molecular Formula

C23H18N6O2

Additionnal Information

GLPG0634 analogue is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.

Storage Conditions

2 years -80 in solvent

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