SC144
Product Specifications
CAS Number
895158-95-9
Target
P-gp
Applications
Neuronal Signaling
Smiles
C1=CN2C3=C (C=C (C=C3) F) N=C (C2=C1) NNC (=O) C4=NC=CN=C4
Molecular Formula
C16H11FN6O
Additionnal Information
SC144 is the first-in-class orally active small-molecule gp130 inhibitor that induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes.
Storage Conditions
2 years -80 in solvent
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