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SC144

Product Specifications

CAS Number

895158-95-9

Target

P-gp

Applications

Neuronal Signaling

Smiles

C1=CN2C3=C (C=C (C=C3) F) N=C (C2=C1) NNC (=O) C4=NC=CN=C4

Molecular Formula

C16H11FN6O

Additionnal Information

SC144 is the first-in-class orally active small-molecule gp130 inhibitor that induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes.

Storage Conditions

2 years -80 in solvent

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